When Robert Langdon wakes up in an Italian hospital with amnesia, he teams up with Sienna Brooks, a doctor he hopes will help him recover his memories. Together, they race across Europe and against the clock to stop a madman from unleashing a global virus that would wipe out half of the world's population.

When respected American religious symbology expert Dr. Robert Langdon is summoned to the Louvre by French Captain Bezu Fache, he soon discovered that he is the number 1 suspect for the murder of a historian Langdon had been scheduled to meet with. Assisted by a French cryptographer and government agent named Sophie, Langdon is challenged to decipher a chain of cryptic codes and puzzles, all the while trying to stay ahead of Fache's lawmen in a chase...