Down on his luck gambler Garry and his hot streak buddy Curtis hit the road for New Orleans, hunting the big payday. On riverboats and racetracks they chase women and thrills before risking it all in the wager of their lives.

A yearly high-stakes poker game between childhood friends turns into chaos when the tech billionaire host unveils an elaborate scheme to seek revenge for the ways they've betrayed him over the years. But as his plans unfold, a group of thieves hatches plans of their breaking into the mansion thinking it is empty. The old friends quickly band together and the years of playing the game help them win their way through a night of terror.